F184-3425 Screening compound: N-(2,4-difluorophenyl)-1-[(2-ethyl-6-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

F184-3425 Screening compound: N-(2,4-difluorophenyl)-1-[(2-ethyl-6-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide
F184-3425 Screening compound: N-(2,4-difluorophenyl)-1-[(2-ethyl-6-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F184-3425
N-(2,4-difluorophenyl)-1-[(2-ethyl-6-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F184-3425

Molecular Formula

C23H25F2N3O5S (C23 H25 F2 N3 O5 S)

Compound Name

N-(2,4-difluorophenyl)-1-[(2-ethyl-6-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-(24-difluorophenyl)-1-[(2-ethyl-6-methyl-3-oxo-34-dihydro-2H-14-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CCC1Oc2cc(S(N(CCC3)CC3C(Nc(ccc(F)c3)c3F)=O)(=O)=O)c(C)cc2NC1=O

InChI

InChI=1S/C23H25F2N3O5S/c1-3-19-23(30)27-18-9-13(2)21(11-20(18)33-19)34(31,32)28-8-4-5-14(12-28)22(29)26-17-7-6-15(24)10-16(17)25/h6-7,9-11,14,19H,3-5,8,12H2,1-2H3,(H,26,29)(H,27,30)

InChI Key

KSDHKOHKQLGTKS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107817

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.089

Distribution Coefficient, logD

2.935

Water Solubility, LogSw

-3.29

Polar Surface Area

87.079

Acid Dissociation Constant (pKa)

7.77

Base Dissociation Constant (pKb)

-2.40

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

39.10

F184-3425 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F184-3425 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F184-3425?
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What is the minimum amount of F184-3425 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F184-3425
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F184-3425
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F184-3425 available by request