F186-0007 Screening compound: N-{4-[2-(azepan-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}benzamide

F186-0007 Screening compound: N-{4-[2-(azepan-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}benzamide
F186-0007 Screening compound: N-{4-[2-(azepan-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-0007
N-{4-[2-(azepan-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-0007

Molecular Formula

C18H21N3O2S (C18 H21 N3 O2 S)

Compound Name

N-{4-[2-(azepan-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl}benzamide

IUPAC name

N-{4-[2-(azepan-1-yl)-2-oxoethyl]-13-thiazol-2-yl}benzamide

SMILES

O=C(Cc1csc(NC(c2ccccc2)=O)n1)N1CCCCCC1

InChI

InChI=1S/C18H21N3O2S/c22-16(21-10-6-1-2-7-11-21)12-15-13-24-18(19-15)20-17(23)14-8-4-3-5-9-14/h3-5,8-9,13H,1-2,6-7,10-12H2,(H,19,20,23)

InChI Key

MXNSTTUCLRWHJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09009254

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

343.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.439

Distribution Coefficient, logD

3.372

Water Solubility, LogSw

-3.65

Polar Surface Area

50.323

Acid Dissociation Constant (pKa)

8.17

Base Dissociation Constant (pKb)

1.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

F186-0007 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

GPCR Targeted Library (31838 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • GPCR
  • Proteases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F186-0007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-0007?
Check Price and Availability of F186-0007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-0007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-0007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-0007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-0007 available by request