F186-0150 Screening compound: N-(4-{[(3-acetamidophenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)benzamide

F186-0150 Screening compound: N-(4-{[(3-acetamidophenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)benzamide
F186-0150 Screening compound: N-(4-{[(3-acetamidophenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-0150
N-(4-{[(3-acetamidophenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-0150

Molecular Formula

C20H18N4O3S (C20 H18 N4 O3 S)

Compound Name

N-(4-{[(3-acetamidophenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)benzamide

IUPAC name

N-(4-{[(3-acetamidophenyl)carbamoyl]methyl}-13-thiazol-2-yl)benzamide

SMILES

CC(Nc1cccc(NC(Cc2csc(NC(c3ccccc3)=O)n2)=O)c1)=O

InChI

InChI=1S/C20H18N4O3S/c1-13(25)21-15-8-5-9-16(10-15)22-18(26)11-17-12-28-20(23-17)24-19(27)14-6-3-2-4-7-14/h2-10,12H,11H2,1H3,(H,21,25)(H,22,26)(H,23,24,27)

InChI Key

DHMPJMCPTJGSCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09240721

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.839

Distribution Coefficient, logD

2.772

Water Solubility, LogSw

-3.37

Polar Surface Area

80.011

Acid Dissociation Constant (pKa)

8.17

Base Dissociation Constant (pKb)

-0.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

F186-0150 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with F186-0150 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-0150?
Check Price and Availability of F186-0150, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-0150 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-0150
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-0150
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-0150 available by request