F186-0302 Screening compound: 4-chloro-N-[4-({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)-1,3-thiazol-2-yl]benzamide

F186-0302 Screening compound: 4-chloro-N-[4-({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)-1,3-thiazol-2-yl]benzamide
F186-0302 Screening compound: 4-chloro-N-[4-({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)-1,3-thiazol-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-0302
4-chloro-N-[4-({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)-1,3-thiazol-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-0302

Molecular Formula

C20H19ClN4O4S2 (C20 H19 ClN4 O4 S2)

Compound Name

4-chloro-N-[4-({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)-1,3-thiazol-2-yl]benzamide

IUPAC name

4-chloro-N-[4-({[2-(4-sulfamoylphenyl)ethyl]carbamoyl}methyl)-13-thiazol-2-yl]benzamide

SMILES

NS(c1ccc(CCNC(Cc2csc(NC(c(cc3)ccc3Cl)=O)n2)=O)cc1)(=O)=O

InChI

InChI=1S/C20H19ClN4O4S2/c21-15-5-3-14(4-6-15)19(27)25-20-24-16(12-30-20)11-18(26)23-10-9-13-1-7-17(8-2-13)31(22,28)29/h1-8,12H,9-11H2,(H,23,26)(H2,22,28,29)(H,24,25,27)

InChI Key

GHMDJDWYXQEQCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09005229

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.98

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.132

Distribution Coefficient, logD

1.741

Water Solubility, LogSw

-3.23

Polar Surface Area

108.516

Acid Dissociation Constant (pKa)

7.23

Base Dissociation Constant (pKb)

-0.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

F186-0302 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F186-0302 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-0302?
Check Price and Availability of F186-0302, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-0302 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-0302
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-0302
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-0302 available by request