F186-0324 Screening compound: N-[4-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1,3-thiazol-2-yl]-4-methoxybenzamide

F186-0324 Screening compound: N-[4-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1,3-thiazol-2-yl]-4-methoxybenzamide
F186-0324 Screening compound: N-[4-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1,3-thiazol-2-yl]-4-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-0324
N-[4-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1,3-thiazol-2-yl]-4-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-0324

Molecular Formula

C20H23N3O5S (C20 H23 N3 O5 S)

Compound Name

N-[4-(2-{1,4-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-1,3-thiazol-2-yl]-4-methoxybenzamide

IUPAC name

N-[4-(2-{14-dioxa-8-azaspiro[4.5]decan-8-yl}-2-oxoethyl)-13-thiazol-2-yl]-4-methoxybenzamide

SMILES

COc(cc1)ccc1C(Nc1nc(CC(N(CC2)CCC22OCCO2)=O)cs1)=O

InChI

InChI=1S/C20H23N3O5S/c1-26-16-4-2-14(3-5-16)18(25)22-19-21-15(13-29-19)12-17(24)23-8-6-20(7-9-23)27-10-11-28-20/h2-5,13H,6-12H2,1H3,(H,21,22,25)

InChI Key

DUPAUEZVBVJDRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08535296

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.093

Distribution Coefficient, logD

2.058

Water Solubility, LogSw

-2.79

Polar Surface Area

71.973

Acid Dissociation Constant (pKa)

8.48

Base Dissociation Constant (pKb)

0.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

F186-0324 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F186-0324 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-0324?
Check Price and Availability of F186-0324, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-0324 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-0324
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-0324
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-0324 available by request