F186-1056 Screening compound: N-[4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-1,3-thiazol-2-yl]furan-2-carboxamide

F186-1056 Screening compound: N-[4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-1,3-thiazol-2-yl]furan-2-carboxamide
F186-1056 Screening compound: N-[4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-1,3-thiazol-2-yl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-1056
N-[4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-1,3-thiazol-2-yl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-1056

Molecular Formula

C18H17N3O4S (C18 H17 N3 O4 S)

Compound Name

N-[4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-1,3-thiazol-2-yl]furan-2-carboxamide

IUPAC name

N-[4-({[(3-methoxyphenyl)methyl]carbamoyl}methyl)-13-thiazol-2-yl]furan-2-carboxamide

SMILES

COc1cccc(CNC(Cc2csc(NC(c3ccco3)=O)n2)=O)c1

InChI

InChI=1S/C18H17N3O4S/c1-24-14-5-2-4-12(8-14)10-19-16(22)9-13-11-26-18(20-13)21-17(23)15-6-3-7-25-15/h2-8,11H,9-10H2,1H3,(H,19,22)(H,20,21,23)

InChI Key

GYTBXCPBDWVYIZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08535538

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.772

Distribution Coefficient, logD

2.747

Water Solubility, LogSw

-3.34

Polar Surface Area

74.193

Acid Dissociation Constant (pKa)

8.62

Base Dissociation Constant (pKb)

-0.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

F186-1056 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F186-1056 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-1056?
Check Price and Availability of F186-1056, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-1056 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-1056
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-1056
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-1056 available by request