F186-1274 Screening compound: N-{4-[(butylcarbamoyl)methyl]-1,3-thiazol-2-yl}-2,2-dimethylpropanamide

F186-1274 Screening compound: N-{4-[(butylcarbamoyl)methyl]-1,3-thiazol-2-yl}-2,2-dimethylpropanamide
F186-1274 Screening compound: N-{4-[(butylcarbamoyl)methyl]-1,3-thiazol-2-yl}-2,2-dimethylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-1274
N-{4-[(butylcarbamoyl)methyl]-1,3-thiazol-2-yl}-2,2-dimethylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-1274

Molecular Formula

C14H23N3O2S (C14 H23 N3 O2 S)

Compound Name

N-{4-[(butylcarbamoyl)methyl]-1,3-thiazol-2-yl}-2,2-dimethylpropanamide

IUPAC name

N-{4-[(butylcarbamoyl)methyl]-13-thiazol-2-yl}-22-dimethylpropanamide

SMILES

CCCCNC(Cc1csc(NC(C(C)(C)C)=O)n1)=O

InChI

InChI=1S/C14H23N3O2S/c1-5-6-7-15-11(18)8-10-9-20-13(16-10)17-12(19)14(2,3)4/h9H,5-8H2,1-4H3,(H,15,18)(H,16,17,19)

InChI Key

WSCISVRKTBJLLJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08535567

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

297.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.647

Distribution Coefficient, logD

2.640

Water Solubility, LogSw

-2.88

Polar Surface Area

58.456

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

4.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

64.30

F186-1274 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with F186-1274 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-1274?
Check Price and Availability of F186-1274, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-1274 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-1274
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-1274
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-1274 available by request