F186-1275 Screening compound: 2,2-dimethyl-N-(4-{[(propan-2-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)propanamide

F186-1275 Screening compound: 2,2-dimethyl-N-(4-{[(propan-2-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)propanamide
F186-1275 Screening compound: 2,2-dimethyl-N-(4-{[(propan-2-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-1275
2,2-dimethyl-N-(4-{[(propan-2-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-1275

Molecular Formula

C13H21N3O2S (C13 H21 N3 O2 S)

Compound Name

2,2-dimethyl-N-(4-{[(propan-2-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)propanamide

IUPAC name

22-dimethyl-N-(4-{[(propan-2-yl)carbamoyl]methyl}-13-thiazol-2-yl)propanamide

SMILES

CC(C)NC(Cc1csc(NC(C(C)(C)C)=O)n1)=O

InChI

InChI=1S/C13H21N3O2S/c1-8(2)14-10(17)6-9-7-19-12(15-9)16-11(18)13(3,4)5/h7-8H,6H2,1-5H3,(H,14,17)(H,15,16,18)

InChI Key

CKVBNNCSXWEYFF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08535568

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

283.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.148

Distribution Coefficient, logD

2.141

Water Solubility, LogSw

-2.57

Polar Surface Area

57.589

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

4.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.50

F186-1275 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with F186-1275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-1275?
Check Price and Availability of F186-1275, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-1275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-1275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-1275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-1275 available by request