F186-1515 Screening compound: N-(4-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide

F186-1515 Screening compound: N-(4-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide
F186-1515 Screening compound: N-(4-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-1515
N-(4-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-1515

Molecular Formula

C16H15N3O4S (C16 H15 N3 O4 S)

Compound Name

N-(4-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide

IUPAC name

N-(4-{[(2H-13-benzodioxol-5-yl)carbamoyl]methyl}-13-thiazol-2-yl)cyclopropanecarboxamide

SMILES

O=C(Cc1csc(NC(C2CC2)=O)n1)Nc(cc1)cc2c1OCO2

InChI

InChI=1S/C16H15N3O4S/c20-14(17-10-3-4-12-13(5-10)23-8-22-12)6-11-7-24-16(18-11)19-15(21)9-1-2-9/h3-5,7,9H,1-2,6,8H2,(H,17,20)(H,18,19,21)

InChI Key

MZPSOHGHDQPWNC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08918877

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.834

Distribution Coefficient, logD

2.832

Water Solubility, LogSw

-3.35

Polar Surface Area

74.388

Acid Dissociation Constant (pKa)

9.69

Base Dissociation Constant (pKb)

1.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

F186-1515 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with F186-1515 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-1515?
Check Price and Availability of F186-1515, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-1515 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-1515
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-1515
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-1515 available by request