F186-1558 Screening compound: N-(4-{[(4-sulfamoylphenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide

F186-1558 Screening compound: N-(4-{[(4-sulfamoylphenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide
F186-1558 Screening compound: N-(4-{[(4-sulfamoylphenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F186-1558
N-(4-{[(4-sulfamoylphenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F186-1558

Molecular Formula

C15H16N4O4S2 (C15 H16 N4 O4 S2)

Compound Name

N-(4-{[(4-sulfamoylphenyl)carbamoyl]methyl}-1,3-thiazol-2-yl)cyclopropanecarboxamide

IUPAC name

N-(4-{[(4-sulfamoylphenyl)carbamoyl]methyl}-13-thiazol-2-yl)cyclopropanecarboxamide

SMILES

NS(c(cc1)ccc1NC(Cc1csc(NC(C2CC2)=O)n1)=O)(=O)=O

InChI

InChI=1S/C15H16N4O4S2/c16-25(22,23)12-5-3-10(4-6-12)17-13(20)7-11-8-24-15(18-11)19-14(21)9-1-2-9/h3-6,8-9H,1-2,7H2,(H,17,20)(H2,16,22,23)(H,18,19,21)

InChI Key

XKIPTYHDISJMHF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08918917

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.45

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.362

Distribution Coefficient, logD

1.360

Water Solubility, LogSw

-2.15

Polar Surface Area

107.875

Acid Dissociation Constant (pKa)

9.69

Base Dissociation Constant (pKb)

-1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

F186-1558 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Immune system
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with F186-1558 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F186-1558?
Check Price and Availability of F186-1558, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F186-1558 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F186-1558
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F186-1558
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F186-1558 available by request