F187-0223 Screening compound: 5-amino-4-(1,3-benzothiazol-2-yl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-2,3-dihydro-1H-pyrrol-3-one

F187-0223 Screening compound: 5-amino-4-(1,3-benzothiazol-2-yl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-2,3-dihydro-1H-pyrrol-3-one
F187-0223 Screening compound: 5-amino-4-(1,3-benzothiazol-2-yl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-2,3-dihydro-1H-pyrrol-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F187-0223
5-amino-4-(1,3-benzothiazol-2-yl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-2,3-dihydro-1H-pyrrol-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F187-0223

Molecular Formula

C24H27N5OS (C24 H27 N5 OS)

Compound Name

5-amino-4-(1,3-benzothiazol-2-yl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-2,3-dihydro-1H-pyrrol-3-one

IUPAC name

5-amino-4-(13-benzothiazol-2-yl)-1-[3-(4-phenylpiperazin-1-yl)propyl]-23-dihydro-1H-pyrrol-3-one

SMILES

NC(N(CCCN(CC1)CCN1c1ccccc1)CC1=O)=C1c1nc(cccc2)c2s1

InChI

InChI=1S/C24H27N5OS/c25-23-22(24-26-19-9-4-5-10-21(19)31-24)20(30)17-29(23)12-6-11-27-13-15-28(16-14-27)18-7-2-1-3-8-18/h1-5,7-10H,6,11-17,25H2

InChI Key

RDWCTFXMFYNVKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107919

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.336

Distribution Coefficient, logD

3.131

Water Solubility, LogSw

-3.58

Polar Surface Area

54.087

Acid Dissociation Constant (pKa)

16.75

Base Dissociation Constant (pKb)

7.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F187-0223 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with F187-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F187-0223?
Check Price and Availability of F187-0223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F187-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F187-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F187-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F187-0223 available by request