F214-0168 Screening compound: 4-propyl-N-(3-pyridylmethyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide

F214-0168 Screening compound: 4-propyl-N-(3-pyridylmethyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide
F214-0168 Screening compound: 4-propyl-N-(3-pyridylmethyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F214-0168
4-propyl-N-(3-pyridylmethyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F214-0168

Molecular Formula

C17H18N4OS (C17 H18 N4 OS)

Compound Name

4-propyl-N-(3-pyridylmethyl)-2-(1H-pyrrol-1-yl)-1,3-thiazole-5-carboxamide

IUPAC name

4-propyl-N-[(pyridin-3-yl)methyl]-2-(1H-pyrrol-1-yl)-13-thiazole-5-carboxamide

SMILES

CCCc1c(C(NCc2cnccc2)=O)sc(-n2cccc2)n1

InChI

InChI=1S/C17H18N4OS/c1-2-6-14-15(23-17(20-14)21-9-3-4-10-21)16(22)19-12-13-7-5-8-18-11-13/h3-5,7-11H,2,6,12H2,1H3,(H,19,22)

InChI Key

CXYXRCRLTJEPOQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18069132

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.227

Distribution Coefficient, logD

3.216

Water Solubility, LogSw

-3.11

Polar Surface Area

49.242

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.53

F214-0168 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F214-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F214-0168?
Check Price and Availability of F214-0168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F214-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F214-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F214-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F214-0168 available by request