F217-0027 Screening compound: 2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-1-(4-phenylpiperazin-1-yl)ethan-1-one

F217-0027 Screening compound: 2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-1-(4-phenylpiperazin-1-yl)ethan-1-one
F217-0027 Screening compound: 2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-1-(4-phenylpiperazin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F217-0027
2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-1-(4-phenylpiperazin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F217-0027

Molecular Formula

C22H26N2O3 (C22 H26 N2 O3)

Compound Name

2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-1-(4-phenylpiperazin-1-yl)ethan-1-one

IUPAC name

2-[(22-dimethyl-23-dihydro-1-benzofuran-7-yl)oxy]-1-(4-phenylpiperazin-1-yl)ethan-1-one

SMILES

CC(C)(Cc1ccc2)Oc1c2OCC(N(CC1)CCN1c1ccccc1)=O

InChI

InChI=1S/C22H26N2O3/c1-22(2)15-17-7-6-10-19(21(17)27-22)26-16-20(25)24-13-11-23(12-14-24)18-8-4-3-5-9-18/h3-10H,11-16H2,1-2H3

InChI Key

BHKXPKMYXLXUTR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06343188

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.222

Distribution Coefficient, logD

3.222

Water Solubility, LogSw

-3.42

Polar Surface Area

33.588

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

6.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

F217-0027 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F217-0027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F217-0027?
Check Price and Availability of F217-0027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F217-0027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F217-0027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F217-0027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F217-0027 available by request