F223-1169 Screening compound: N-(6-{[(4-chloro-2,5-dimethoxyphenyl)carbamoyl]methyl}-1,3-benzothiazol-2-yl)-2-methylpropanamide

F223-1169 Screening compound: N-(6-{[(4-chloro-2,5-dimethoxyphenyl)carbamoyl]methyl}-1,3-benzothiazol-2-yl)-2-methylpropanamide
F223-1169 Screening compound: N-(6-{[(4-chloro-2,5-dimethoxyphenyl)carbamoyl]methyl}-1,3-benzothiazol-2-yl)-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F223-1169
N-(6-{[(4-chloro-2,5-dimethoxyphenyl)carbamoyl]methyl}-1,3-benzothiazol-2-yl)-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F223-1169

Molecular Formula

C21H22ClN3O4S (C21 H22 ClN3 O4 S)

Compound Name

N-(6-{[(4-chloro-2,5-dimethoxyphenyl)carbamoyl]methyl}-1,3-benzothiazol-2-yl)-2-methylpropanamide

IUPAC name

N-(6-{[(4-chloro-25-dimethoxyphenyl)carbamoyl]methyl}-13-benzothiazol-2-yl)-2-methylpropanamide

SMILES

CC(C)C(Nc1nc(ccc(CC(Nc(c(OC)c2)cc(OC)c2Cl)=O)c2)c2s1)=O

InChI

InChI=1S/C21H22ClN3O4S/c1-11(2)20(27)25-21-24-14-6-5-12(7-18(14)30-21)8-19(26)23-15-10-16(28-3)13(22)9-17(15)29-4/h5-7,9-11H,8H2,1-4H3,(H,23,26)(H,24,25,27)

InChI Key

HBGQBDHEMBBYDH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14945363

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.94

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.366

Distribution Coefficient, logD

4.271

Water Solubility, LogSw

-4.48

Polar Surface Area

70.803

Acid Dissociation Constant (pKa)

8.01

Base Dissociation Constant (pKb)

0.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

F223-1169 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F223-1169 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F223-1169?
Check Price and Availability of F223-1169, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F223-1169 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F223-1169
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F223-1169
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F223-1169 available by request