F235-1526 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(4-methylphenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

F235-1526 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(4-methylphenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide
F235-1526 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(4-methylphenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F235-1526
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(4-methylphenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F235-1526

Molecular Formula

C25H22N2O5 (C25 H22 N2 O5)

Compound Name

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(4-methylphenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

IUPAC name

N-(23-dihydro-14-benzodioxin-6-yl)-1-(4-methylphenyl)-25-dioxo-125678-hexahydroquinoline-3-carboxamide

SMILES

Cc(cc1)ccc1N(C(CCC1)=C(C=C2C(Nc(cc3)cc4c3OCCO4)=O)C1=O)C2=O

InChI

InChI=1S/C25H22N2O5/c1-15-5-8-17(9-6-15)27-20-3-2-4-21(28)18(20)14-19(25(27)30)24(29)26-16-7-10-22-23(13-16)32-12-11-31-22/h5-10,13-14H,2-4,11-12H2,1H3,(H,26,29)

InChI Key

VSUHYIUMCMEDKK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03011310

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.285

Distribution Coefficient, logD

2.181

Water Solubility, LogSw

-2.96

Polar Surface Area

67.494

Acid Dissociation Constant (pKa)

7.97

Base Dissociation Constant (pKb)

-2.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

F235-1526 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F235-1526 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F235-1526?
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What is the minimum amount of F235-1526 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F235-1526
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F235-1526
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F235-1526 available by request