F254-3516 Screening compound: N-(3-chloro-4-methoxyphenyl)-7-(4-fluorophenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

F254-3516 Screening compound: N-(3-chloro-4-methoxyphenyl)-7-(4-fluorophenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
F254-3516 Screening compound: N-(3-chloro-4-methoxyphenyl)-7-(4-fluorophenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F254-3516
N-(3-chloro-4-methoxyphenyl)-7-(4-fluorophenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F254-3516

Molecular Formula

C22H20ClFN4O (C22 H20 ClFN4 O)

Compound Name

N-(3-chloro-4-methoxyphenyl)-7-(4-fluorophenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

IUPAC name

N-(3-chloro-4-methoxyphenyl)-7-(4-fluorophenyl)-256-trimethyl-7H-pyrrolo[23-d]pyrimidin-4-amine

SMILES

Cc(c1c2nc(C)nc1Nc(cc1)cc(Cl)c1OC)c(C)n2-c(cc1)ccc1F

InChI

InChI=1S/C22H20ClFN4O/c1-12-13(2)28(17-8-5-15(24)6-9-17)22-20(12)21(25-14(3)26-22)27-16-7-10-19(29-4)18(23)11-16/h5-11H,1-4H3,(H,25,26,27)

InChI Key

PUYIPOZQBUYSRK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27109686

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.88

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.604

Distribution Coefficient, logD

4.635

Water Solubility, LogSw

-6.09

Polar Surface Area

38.408

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

8.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

F254-3516 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F254-3516 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F254-3516?
Check Price and Availability of F254-3516, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F254-3516 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F254-3516
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F254-3516
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F254-3516 available by request