F255-0577 Screening compound: N-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

F255-0577 Screening compound: N-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
F255-0577 Screening compound: N-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F255-0577
N-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F255-0577

Molecular Formula

C28H27N5O2 (C28 H27 N5 O2)

Compound Name

N-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

IUPAC name

N-{4-[2-(5-methyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(4-methylphenyl)-124-oxadiazol-5-yl]propanamide

SMILES

Cc(cc1)ccc1-c1noc(CCC(Nc2ccc(CCc3nc(cc(C)cc4)c4[nH]3)cc2)=O)n1

InChI

InChI=1S/C28H27N5O2/c1-18-3-9-21(10-4-18)28-32-27(35-33-28)16-15-26(34)29-22-11-6-20(7-12-22)8-14-25-30-23-13-5-19(2)17-24(23)31-25/h3-7,9-13,17H,8,14-16H2,1-2H3,(H,29,34)(H,30,31)

InChI Key

RVBVXLMYDRURQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27109753

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.387

Distribution Coefficient, logD

6.371

Water Solubility, LogSw

-5.39

Polar Surface Area

74.469

Acid Dissociation Constant (pKa)

13.72

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

F255-0577 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Lipid Metabolism Library (9174 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F255-0577 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F255-0577?
Check Price and Availability of F255-0577, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F255-0577 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F255-0577
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F255-0577
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F255-0577 available by request