F257-0818 Screening compound: N-{2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methyl-2-phenoxypropanamide

F257-0818 Screening compound: N-{2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methyl-2-phenoxypropanamide
F257-0818 Screening compound: N-{2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methyl-2-phenoxypropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F257-0818
N-{2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methyl-2-phenoxypropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F257-0818

Molecular Formula

C20H20FN3O3 (C20 H20 FN3 O3)

Compound Name

N-{2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methyl-2-phenoxypropanamide

IUPAC name

N-{2-[5-(2-fluorophenyl)-124-oxadiazol-3-yl]ethyl}-N-methyl-2-phenoxypropanamide

SMILES

CC(C(N(C)CCc1noc(-c(cccc2)c2F)n1)=O)Oc1ccccc1

InChI

InChI=1S/C20H20FN3O3/c1-14(26-15-8-4-3-5-9-15)20(25)24(2)13-12-18-22-19(27-23-18)16-10-6-7-11-17(16)21/h3-11,14H,12-13H2,1-2H3/t14-/m0/s1

InChI Key

HFAMQAAEEZFADN-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27110403

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.296

Distribution Coefficient, logD

3.296

Water Solubility, LogSw

-3.74

Polar Surface Area

55.824

Acid Dissociation Constant (pKa)

22.03

Base Dissociation Constant (pKb)

0.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

F257-0818 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F257-0818 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F257-0818?
Check Price and Availability of F257-0818, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F257-0818 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F257-0818
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F257-0818
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F257-0818 available by request