F259-0641 Screening compound: N-(2-acetamido-4-methoxy-1,3-benzothiazol-6-yl)-1H,4H,5H-benzo[g]indazole-3-carboxamide

F259-0641 Screening compound: N-(2-acetamido-4-methoxy-1,3-benzothiazol-6-yl)-1H,4H,5H-benzo[g]indazole-3-carboxamide
F259-0641 Screening compound: N-(2-acetamido-4-methoxy-1,3-benzothiazol-6-yl)-1H,4H,5H-benzo[g]indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F259-0641
N-(2-acetamido-4-methoxy-1,3-benzothiazol-6-yl)-1H,4H,5H-benzo[g]indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F259-0641

Molecular Formula

C22H19N5O3S (C22 H19 N5 O3 S)

Compound Name

N-(2-acetamido-4-methoxy-1,3-benzothiazol-6-yl)-1H,4H,5H-benzo[g]indazole-3-carboxamide

IUPAC name

N-(2-acetamido-4-methoxy-13-benzothiazol-6-yl)-1H4H5H-benzo[g]indazole-3-carboxamide

SMILES

CC(Nc1nc(c(OC)cc(NC(c2n[nH]c-3c2CCc2c3cccc2)=O)c2)c2s1)=O

InChI

InChI=1S/C22H19N5O3S/c1-11(28)23-22-25-20-16(30-2)9-13(10-17(20)31-22)24-21(29)19-15-8-7-12-5-3-4-6-14(12)18(15)26-27-19/h3-6,9-10H,7-8H2,1-2H3,(H,24,29)(H,26,27)(H,23,25,28)

InChI Key

HGSYPDWUFKXUHC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14946613

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.981

Distribution Coefficient, logD

3.980

Water Solubility, LogSw

-4.26

Polar Surface Area

88.796

Acid Dissociation Constant (pKa)

9.78

Base Dissociation Constant (pKb)

0.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

F259-0641 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F259-0641 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F259-0641?
Check Price and Availability of F259-0641, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F259-0641 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F259-0641
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F259-0641
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F259-0641 available by request