F266-0127 Screening compound: N-[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]cyclohexanecarboxamide

F266-0127 Screening compound: N-[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]cyclohexanecarboxamide
F266-0127 Screening compound: N-[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]cyclohexanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F266-0127
N-[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]cyclohexanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F266-0127

Molecular Formula

C22H20ClNO3 (C22 H20 ClNO3)

Compound Name

N-[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]cyclohexanecarboxamide

IUPAC name

N-[2-(4-chlorobenzoyl)-1-benzofuran-3-yl]cyclohexanecarboxamide

SMILES

O=C(C1CCCCC1)Nc1c(C(c(cc2)ccc2Cl)=O)oc2c1cccc2

InChI

InChI=1S/C22H20ClNO3/c23-16-12-10-14(11-13-16)20(25)21-19(17-8-4-5-9-18(17)27-21)24-22(26)15-6-2-1-3-7-15/h4-5,8-13,15H,1-3,6-7H2,(H,24,26)

InChI Key

IAQXIFDUXHAPHP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09241050

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.86

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.573

Distribution Coefficient, logD

5.568

Water Solubility, LogSw

-6.15

Polar Surface Area

44.119

Acid Dissociation Constant (pKa)

9.34

Base Dissociation Constant (pKb)

-1.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

F266-0127 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with F266-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F266-0127?
Check Price and Availability of F266-0127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F266-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F266-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F266-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F266-0127 available by request