F269-0292 Screening compound: (2E)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide

F269-0292 Screening compound: (2E)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
F269-0292 Screening compound: (2E)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F269-0292
(2E)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F269-0292

Molecular Formula

C23H27N5O5 (C23 H27 N5 O5)

Compound Name

(2E)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide

IUPAC name

(2E)-N-[3-methyl-1-(6-oxo-4-propyl-16-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-3-(345-trimethoxyphenyl)prop-2-enamide

SMILES

CCCC(N=C(N1)n2nc(C)cc2NC(/C=C/c(cc2OC)cc(OC)c2OC)=O)=CC1=O

InChI

InChI=1S/C23H27N5O5/c1-6-7-16-13-21(30)26-23(24-16)28-19(10-14(2)27-28)25-20(29)9-8-15-11-17(31-3)22(33-5)18(12-15)32-4/h8-13H,6-7H2,1-5H3,(H,25,29)(H,24,26,30)

InChI Key

BRUWJPJHXRQXLR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08536797

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.495

Distribution Coefficient, logD

1.921

Water Solubility, LogSw

-2.79

Polar Surface Area

95.007

Acid Dissociation Constant (pKa)

6.96

Base Dissociation Constant (pKb)

-2.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

F269-0292 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with F269-0292 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F269-0292?
Check Price and Availability of F269-0292, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F269-0292 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F269-0292
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F269-0292
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F269-0292 available by request