F269-0335 Screening compound: 1-(4-chlorophenyl)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-5-oxopyrrolidine-3-carboxamide

F269-0335 Screening compound: 1-(4-chlorophenyl)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-5-oxopyrrolidine-3-carboxamide
F269-0335 Screening compound: 1-(4-chlorophenyl)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F269-0335
1-(4-chlorophenyl)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F269-0335

Molecular Formula

C22H23ClN6O3 (C22 H23 ClN6 O3)

Compound Name

1-(4-chlorophenyl)-N-[3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-5-oxopyrrolidine-3-carboxamide

IUPAC name

1-(4-chlorophenyl)-N-[3-methyl-1-(6-oxo-4-propyl-16-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl]-5-oxopyrrolidine-3-carboxamide

SMILES

CCCC(N=C(N1)n2nc(C)cc2NC(C(CC2=O)CN2c(cc2)ccc2Cl)=O)=CC1=O

InChI

InChI=1S/C22H23ClN6O3/c1-3-4-16-11-19(30)26-22(24-16)29-18(9-13(2)27-29)25-21(32)14-10-20(31)28(12-14)17-7-5-15(23)6-8-17/h5-9,11,14H,3-4,10,12H2,1-2H3,(H,25,32)(H,24,26,30)/t14-/m1/s1

InChI Key

KQBXLCJOBRCJBD-CQSZACIVSA-N

MDL Number (MFCD)

MFCD08536834

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.106

Distribution Coefficient, logD

1.872

Water Solubility, LogSw

-3.23

Polar Surface Area

88.993

Acid Dissociation Constant (pKa)

7.55

Base Dissociation Constant (pKb)

-1.25

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

F269-0335 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Arginase Targeted Library (2009 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Male
  • Cardiovascular
Targets:
  • Others

References: we are preparing a list of scientific research reports with F269-0335 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F269-0335?
Check Price and Availability of F269-0335, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F269-0335 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F269-0335
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F269-0335
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F269-0335 available by request