F270-0653 Screening compound: 2-{3,4-dimethyl-7-oxo-6H,7H-[1,2]oxazolo[3,4-d]pyridazin-6-yl}-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}acetamide

F270-0653 Screening compound: 2-{3,4-dimethyl-7-oxo-6H,7H-[1,2]oxazolo[3,4-d]pyridazin-6-yl}-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}acetamide
F270-0653 Screening compound: 2-{3,4-dimethyl-7-oxo-6H,7H-[1,2]oxazolo[3,4-d]pyridazin-6-yl}-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F270-0653
2-{3,4-dimethyl-7-oxo-6H,7H-[1,2]oxazolo[3,4-d]pyridazin-6-yl}-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F270-0653

Molecular Formula

C22H27FN6O3 (C22 H27 FN6 O3)

Compound Name

2-{3,4-dimethyl-7-oxo-6H,7H-[1,2]oxazolo[3,4-d]pyridazin-6-yl}-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}acetamide

IUPAC name

2-{34-dimethyl-7-oxo-6H7H-[12]oxazolo[34-d]pyridazin-6-yl}-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}acetamide

SMILES

Cc(onc12)c2C(C)=NN(CC(NCCCN(CC2)CCN2c(cc2)ccc2F)=O)C1=O

InChI

InChI=1S/C22H27FN6O3/c1-15-20-16(2)32-26-21(20)22(31)29(25-15)14-19(30)24-8-3-9-27-10-12-28(13-11-27)18-6-4-17(23)5-7-18/h4-7H,3,8-14H2,1-2H3,(H,24,30)

InChI Key

DAECDXBTVFZSPK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27111206

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.987

Distribution Coefficient, logD

0.401

Water Solubility, LogSw

-2.18

Polar Surface Area

80.518

Acid Dissociation Constant (pKa)

16.11

Base Dissociation Constant (pKb)

7.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

F270-0653 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F270-0653 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F270-0653?
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What is the minimum amount of F270-0653 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F270-0653
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F270-0653
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F270-0653 available by request