F281-0143 Screening compound: N-(2,1,3-benzothiadiazol-4-yl)-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide

F281-0143 Screening compound: N-(2,1,3-benzothiadiazol-4-yl)-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide
F281-0143 Screening compound: N-(2,1,3-benzothiadiazol-4-yl)-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F281-0143
N-(2,1,3-benzothiadiazol-4-yl)-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F281-0143

Molecular Formula

C21H20N4OS (C21 H20 N4 OS)

Compound Name

N-(2,1,3-benzothiadiazol-4-yl)-3-(2,3,4,9-tetrahydro-1H-carbazol-9-yl)propanamide

IUPAC name

N-(213-benzothiadiazol-4-yl)-3-(2349-tetrahydro-1H-carbazol-9-yl)propanamide

SMILES

O=C(CCn1c(cccc2)c2c2c1CCCC2)Nc1cccc2nsnc12

InChI

InChI=1S/C21H20N4OS/c26-20(22-16-8-5-9-17-21(16)24-27-23-17)12-13-25-18-10-3-1-6-14(18)15-7-2-4-11-19(15)25/h1,3,5-6,8-10H,2,4,7,11-13H2,(H,22,26)

InChI Key

DJZHCIQUHBCEJB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14947105

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.630

Distribution Coefficient, logD

4.629

Water Solubility, LogSw

-4.54

Polar Surface Area

44.727

Acid Dissociation Constant (pKa)

10.09

Base Dissociation Constant (pKb)

-1.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

F281-0143 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F281-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F281-0143?
Check Price and Availability of F281-0143, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F281-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F281-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F281-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F281-0143 available by request