F282-0008 Screening compound: 6-methyl-5-(piperidine-1-sulfonyl)-N-[3-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidin-4-amine

F282-0008 Screening compound: 6-methyl-5-(piperidine-1-sulfonyl)-N-[3-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidin-4-amine
F282-0008 Screening compound: 6-methyl-5-(piperidine-1-sulfonyl)-N-[3-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F282-0008
6-methyl-5-(piperidine-1-sulfonyl)-N-[3-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F282-0008

Molecular Formula

C19H19F3N4O2S2 (C19 H19 F3 N4 O2 S2)

Compound Name

6-methyl-5-(piperidine-1-sulfonyl)-N-[3-(trifluoromethyl)phenyl]thieno[2,3-d]pyrimidin-4-amine

IUPAC name

6-methyl-5-(piperidine-1-sulfonyl)-N-[3-(trifluoromethyl)phenyl]thieno[23-d]pyrimidin-4-amine

SMILES

Cc(sc1ncnc(Nc2cc(C(F)(F)F)ccc2)c11)c1S(N1CCCCC1)(=O)=O

InChI

InChI=1S/C19H19F3N4O2S2/c1-12-16(30(27,28)26-8-3-2-4-9-26)15-17(23-11-24-18(15)29-12)25-14-7-5-6-13(10-14)19(20,21)22/h5-7,10-11H,2-4,8-9H2,1H3,(H,23,24,25)

InChI Key

MBYVMFHLBJUNLU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14947110

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.821

Distribution Coefficient, logD

4.728

Water Solubility, LogSw

-4.80

Polar Surface Area

62.416

Acid Dissociation Constant (pKa)

13.68

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

F282-0008 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with F282-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F282-0008?
Check Price and Availability of F282-0008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F282-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F282-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F282-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F282-0008 available by request