F282-0012 Screening compound: N-(3-chloro-4-fluorophenyl)-6-methyl-5-(piperidine-1-sulfonyl)thieno[2,3-d]pyrimidin-4-amine

F282-0012 Screening compound: N-(3-chloro-4-fluorophenyl)-6-methyl-5-(piperidine-1-sulfonyl)thieno[2,3-d]pyrimidin-4-amine
F282-0012 Screening compound: N-(3-chloro-4-fluorophenyl)-6-methyl-5-(piperidine-1-sulfonyl)thieno[2,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F282-0012
N-(3-chloro-4-fluorophenyl)-6-methyl-5-(piperidine-1-sulfonyl)thieno[2,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F282-0012

Molecular Formula

C18H18ClFN4O2S2 (C18 H18 ClFN4 O2 S2)

Compound Name

N-(3-chloro-4-fluorophenyl)-6-methyl-5-(piperidine-1-sulfonyl)thieno[2,3-d]pyrimidin-4-amine

IUPAC name

N-(3-chloro-4-fluorophenyl)-6-methyl-5-(piperidine-1-sulfonyl)thieno[23-d]pyrimidin-4-amine

SMILES

Cc(sc1c2c(Nc(cc3)cc(Cl)c3F)ncn1)c2S(N1CCCCC1)(=O)=O

InChI

InChI=1S/C18H18ClFN4O2S2/c1-11-16(28(25,26)24-7-3-2-4-8-24)15-17(21-10-22-18(15)27-11)23-12-5-6-14(20)13(19)9-12/h5-6,9-10H,2-4,7-8H2,1H3,(H,21,22,23)

InChI Key

VJQGVVJGYVGTKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14947113

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.95

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.508

Distribution Coefficient, logD

4.490

Water Solubility, LogSw

-4.62

Polar Surface Area

62.416

Acid Dissociation Constant (pKa)

12.41

Base Dissociation Constant (pKb)

6.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F282-0012 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Lipid Metabolism Library (9174 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cardiovascular
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F282-0012 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F282-0012?
Check Price and Availability of F282-0012, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F282-0012 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F282-0012
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F282-0012
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F282-0012 available by request