F283-0912 Screening compound: 2,8-dimethyl-4-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinoline

F283-0912 Screening compound: 2,8-dimethyl-4-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinoline
F283-0912 Screening compound: 2,8-dimethyl-4-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound F283-0912
2,8-dimethyl-4-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F283-0912

Molecular Formula

C23H22F3N3O (C23 H22 F3 N3 O)

Compound Name

2,8-dimethyl-4-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinoline

IUPAC name

28-dimethyl-4-{4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl}quinoline

SMILES

Cc1c2nc(C)cc(C(N(CC3)CCN3c3cccc(C(F)(F)F)c3)=O)c2ccc1

InChI

InChI=1S/C23H22F3N3O/c1-15-5-3-8-19-20(13-16(2)27-21(15)19)22(30)29-11-9-28(10-12-29)18-7-4-6-17(14-18)23(24,25)26/h3-8,13-14H,9-12H2,1-2H3

InChI Key

JZDKBUGUZONBOP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14947234

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.666

Distribution Coefficient, logD

4.664

Water Solubility, LogSw

-4.55

Polar Surface Area

29.055

Acid Dissociation Constant (pKa)

23.92

Base Dissociation Constant (pKb)

5.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

F283-0912 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with F283-0912 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F283-0912?
Check Price and Availability of F283-0912, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F283-0912 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F283-0912
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F283-0912
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F283-0912 available by request