F284-0034 Screening compound: N-(5-chloro-2-methylphenyl)-2-oxo-1,2,3',6',7',7'a-hexahydro-1'H-spiro[indole-3,5'-pyrrolo[1,2-c][1,3]thiazole]-6'-carboxamide

F284-0034 Screening compound: N-(5-chloro-2-methylphenyl)-2-oxo-1,2,3',6',7',7'a-hexahydro-1'H-spiro[indole-3,5'-pyrrolo[1,2-c][1,3]thiazole]-6'-carboxamide
F284-0034 Screening compound: N-(5-chloro-2-methylphenyl)-2-oxo-1,2,3',6',7',7'a-hexahydro-1'H-spiro[indole-3,5'-pyrrolo[1,2-c][1,3]thiazole]-6'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F284-0034
N-(5-chloro-2-methylphenyl)-2-oxo-1,2,3',6',7',7'a-hexahydro-1'H-spiro[indole-3,5'-pyrrolo[1,2-c][1,3]thiazole]-6'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F284-0034

Molecular Formula

C21H20ClN3O2S (C21 H20 ClN3 O2 S)

Compound Name

N-(5-chloro-2-methylphenyl)-2-oxo-1,2,3',6',7',7'a-hexahydro-1'H-spiro[indole-3,5'-pyrrolo[1,2-c][1,3]thiazole]-6'-carboxamide

IUPAC name

N-(5-chloro-2-methylphenyl)-2-oxo-123'6'7'7'a-hexahydro-1'H-spiro[indole-35'-pyrrolo[12-c][13]thiazole]-6'-carboxamide

SMILES

Cc(ccc(Cl)c1)c1NC(C(C1)C(c(cccc2)c2N2)(C2=O)N2C1CSC2)=O

InChI

InChI=1S/C21H20ClN3O2S/c1-12-6-7-13(22)8-18(12)23-19(26)16-9-14-10-28-11-25(14)21(16)15-4-2-3-5-17(15)24-20(21)27/h2-8,14,16H,9-11H2,1H3,(H,23,26)(H,24,27)

InChI Key

NMVUOEISPKNHFL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27111599

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.934

Distribution Coefficient, logD

3.929

Water Solubility, LogSw

-4.38

Polar Surface Area

51.158

Acid Dissociation Constant (pKa)

9.28

Base Dissociation Constant (pKb)

-1.16

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

33.30

F284-0034 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral Library (67538 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Spiro Library (21655 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with F284-0034 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F284-0034?
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What is the minimum amount of F284-0034 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F284-0034
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F284-0034
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F284-0034 available by request