F290-0303 Screening compound: 5-(2,5-dimethoxybenzenesulfonamido)-2-[4-(pyridin-2-yl)piperazin-1-yl]benzoic acid

F290-0303 Screening compound: 5-(2,5-dimethoxybenzenesulfonamido)-2-[4-(pyridin-2-yl)piperazin-1-yl]benzoic acid
F290-0303 Screening compound: 5-(2,5-dimethoxybenzenesulfonamido)-2-[4-(pyridin-2-yl)piperazin-1-yl]benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound F290-0303
5-(2,5-dimethoxybenzenesulfonamido)-2-[4-(pyridin-2-yl)piperazin-1-yl]benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F290-0303

Molecular Formula

C24H26N4O6S (C24 H26 N4 O6 S)

Compound Name

5-(2,5-dimethoxybenzenesulfonamido)-2-[4-(pyridin-2-yl)piperazin-1-yl]benzoic acid

IUPAC name

5-(25-dimethoxybenzenesulfonamido)-2-[4-(pyridin-2-yl)piperazin-1-yl]benzoic acid

SMILES

COc(cc1)cc(S(Nc(cc2)cc(C(O)=O)c2N(CC2)CCN2c2ncccc2)(=O)=O)c1OC

InChI

InChI=1S/C24H26N4O6S/c1-33-18-7-9-21(34-2)22(16-18)35(31,32)26-17-6-8-20(19(15-17)24(29)30)27-11-13-28(14-12-27)23-5-3-4-10-25-23/h3-10,15-16,26H,11-14H2,1-2H3,(H,29,30)

InChI Key

LGOUNFMZWQKKKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27112105

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.895

Distribution Coefficient, logD

1.779

Water Solubility, LogSw

-4.02

Polar Surface Area

99.394

Acid Dissociation Constant (pKa)

5.29

Base Dissociation Constant (pKb)

5.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F290-0303 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Eccentric PPI Library (11937 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with F290-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F290-0303?
Check Price and Availability of F290-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F290-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F290-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F290-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F290-0303 available by request