F305-1612 Screening compound: 8-{1-[6-(3,4-dimethylphenyl)pyridazin-3-yl]piperidine-3-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

F305-1612 Screening compound: 8-{1-[6-(3,4-dimethylphenyl)pyridazin-3-yl]piperidine-3-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane
F305-1612 Screening compound: 8-{1-[6-(3,4-dimethylphenyl)pyridazin-3-yl]piperidine-3-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound F305-1612
8-{1-[6-(3,4-dimethylphenyl)pyridazin-3-yl]piperidine-3-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F305-1612

Molecular Formula

C25H32N4O3 (C25 H32 N4 O3)

Compound Name

8-{1-[6-(3,4-dimethylphenyl)pyridazin-3-yl]piperidine-3-carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{1-[6-(34-dimethylphenyl)pyridazin-3-yl]piperidine-3-carbonyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

Cc(cc1)c(C)cc1-c(cc1)nnc1N(CCC1)CC1C(N(CC1)CCC11OCCO1)=O

InChI

InChI=1S/C25H32N4O3/c1-18-5-6-20(16-19(18)2)22-7-8-23(27-26-22)29-11-3-4-21(17-29)24(30)28-12-9-25(10-13-28)31-14-15-32-25/h5-8,16,21H,3-4,9-15,17H2,1-2H3/t21-/m0/s1

InChI Key

FUVFUMNMGSRVIH-NRFANRHFSA-N

MDL Number (MFCD)

MFCD22589327

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.281

Distribution Coefficient, logD

3.269

Water Solubility, LogSw

-3.20

Polar Surface Area

55.644

Acid Dissociation Constant (pKa)

22.75

Base Dissociation Constant (pKb)

5.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

56.00

F305-1612 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F305-1612 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F305-1612?
Check Price and Availability of F305-1612, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F305-1612 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F305-1612
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F305-1612
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F305-1612 available by request