F305-1637 Screening compound: 3-(3,4-dimethylphenyl)-6-{3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

F305-1637 Screening compound: 3-(3,4-dimethylphenyl)-6-{3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine
F305-1637 Screening compound: 3-(3,4-dimethylphenyl)-6-{3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F305-1637
3-(3,4-dimethylphenyl)-6-{3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F305-1637

Molecular Formula

C29H35N5O2 (C29 H35 N5 O2)

Compound Name

3-(3,4-dimethylphenyl)-6-{3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

IUPAC name

3-(34-dimethylphenyl)-6-{3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

SMILES

Cc(cc1)c(C)cc1-c(cc1)nnc1N(CCC1)CC1C(N(CC1)CCN1c(cc1)ccc1OC)=O

InChI

InChI=1S/C29H35N5O2/c1-21-6-7-23(19-22(21)2)27-12-13-28(31-30-27)34-14-4-5-24(20-34)29(35)33-17-15-32(16-18-33)25-8-10-26(36-3)11-9-25/h6-13,19,24H,4-5,14-18,20H2,1-3H3/t24-/m0/s1

InChI Key

FZCAYSKLBJWJGT-DEOSSOPVSA-N

MDL Number (MFCD)

MFCD22589330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.958

Distribution Coefficient, logD

4.946

Water Solubility, LogSw

-4.73

Polar Surface Area

52.012

Acid Dissociation Constant (pKa)

22.75

Base Dissociation Constant (pKb)

5.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.40

F305-1637 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F305-1637 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F305-1637?
Check Price and Availability of F305-1637, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F305-1637 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F305-1637
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F305-1637
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F305-1637 available by request