F318-0353 Screening compound: 4-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoxalin-2-one

F318-0353 Screening compound: 4-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoxalin-2-one
F318-0353 Screening compound: 4-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoxalin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F318-0353
4-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoxalin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F318-0353

Molecular Formula

C16H14N4O4S2 (C16 H14 N4 O4 S2)

Compound Name

4-{[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoxalin-2-one

IUPAC name

4-{[2-methyl-5-(5-methyl-124-oxadiazol-3-yl)thiophen-3-yl]sulfonyl}-1234-tetrahydroquinoxalin-2-one

SMILES

Cc(sc(-c1noc(C)n1)c1)c1S(N(C1)c(cccc2)c2NC1=O)(=O)=O

InChI

InChI=1S/C16H14N4O4S2/c1-9-14(7-13(25-9)16-17-10(2)24-19-16)26(22,23)20-8-15(21)18-11-5-3-4-6-12(11)20/h3-7H,8H2,1-2H3,(H,18,21)

InChI Key

ZJEBYBUDBHIGML-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27114854

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.44

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.420

Distribution Coefficient, logD

2.420

Water Solubility, LogSw

-2.99

Polar Surface Area

88.148

Acid Dissociation Constant (pKa)

11.13

Base Dissociation Constant (pKb)

-2.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

F318-0353 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with F318-0353 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F318-0353?
Check Price and Availability of F318-0353, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F318-0353 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F318-0353
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F318-0353
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F318-0353 available by request