F318-0821 Screening compound: N-(4-chloro-2-methylphenyl)-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophene-3-sulfonamide

F318-0821 Screening compound: N-(4-chloro-2-methylphenyl)-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophene-3-sulfonamide
F318-0821 Screening compound: N-(4-chloro-2-methylphenyl)-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophene-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F318-0821
N-(4-chloro-2-methylphenyl)-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophene-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F318-0821

Molecular Formula

C17H16ClN3O3S2 (C17 H16 ClN3 O3 S2)

Compound Name

N-(4-chloro-2-methylphenyl)-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methylthiophene-3-sulfonamide

IUPAC name

N-(4-chloro-2-methylphenyl)-5-(5-cyclopropyl-124-oxadiazol-3-yl)-2-methylthiophene-3-sulfonamide

SMILES

Cc(sc(-c1noc(C2CC2)n1)c1)c1S(Nc(cc1)c(C)cc1Cl)(=O)=O

InChI

InChI=1S/C17H16ClN3O3S2/c1-9-7-12(18)5-6-13(9)21-26(22,23)15-8-14(25-10(15)2)16-19-17(24-20-16)11-3-4-11/h5-8,11,21H,3-4H2,1-2H3

InChI Key

HOHQMEUCLHIORD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27114947

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.600

Distribution Coefficient, logD

5.354

Water Solubility, LogSw

-5.92

Polar Surface Area

73.138

Acid Dissociation Constant (pKa)

7.52

Base Dissociation Constant (pKb)

-0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

F318-0821 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F318-0821 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F318-0821?
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What is the minimum amount of F318-0821 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F318-0821
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F318-0821
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F318-0821 available by request