F324-1246 Screening compound: 1-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-3,3,5-trimethyl-2,3-dihydro-1H-indol-2-one

F324-1246 Screening compound: 1-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-3,3,5-trimethyl-2,3-dihydro-1H-indol-2-one
F324-1246 Screening compound: 1-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-3,3,5-trimethyl-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F324-1246
1-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-3,3,5-trimethyl-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F324-1246

Molecular Formula

C24H29N3O3 (C24 H29 N3 O3)

Compound Name

1-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-3,3,5-trimethyl-2,3-dihydro-1H-indol-2-one

IUPAC name

1-{2-[4-(3-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-335-trimethyl-23-dihydro-1H-indol-2-one

SMILES

CC(C)(c(cc(C)cc1)c1N1CC(N(CC2)CCN2c2cc(OC)ccc2)=O)C1=O

InChI

InChI=1S/C24H29N3O3/c1-17-8-9-21-20(14-17)24(2,3)23(29)27(21)16-22(28)26-12-10-25(11-13-26)18-6-5-7-19(15-18)30-4/h5-9,14-15H,10-13,16H2,1-4H3

InChI Key

XZZVYRQSDHGFCK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27116447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.358

Distribution Coefficient, logD

3.358

Water Solubility, LogSw

-3.66

Polar Surface Area

42.904

Acid Dissociation Constant (pKa)

24.16

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

F324-1246 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F324-1246 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F324-1246?
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What is the minimum amount of F324-1246 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F324-1246
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F324-1246
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F324-1246 available by request