F324-1265 Screening compound: 3,3,5-trimethyl-1-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one

F324-1265 Screening compound: 3,3,5-trimethyl-1-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one
F324-1265 Screening compound: 3,3,5-trimethyl-1-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F324-1265
3,3,5-trimethyl-1-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F324-1265

Molecular Formula

C22H24N2O2 (C22 H24 N2 O2)

Compound Name

3,3,5-trimethyl-1-[2-oxo-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]-2,3-dihydro-1H-indol-2-one

IUPAC name

335-trimethyl-1-[2-oxo-2-(1234-tetrahydroisoquinolin-2-yl)ethyl]-23-dihydro-1H-indol-2-one

SMILES

CC(C)(c(cc(C)cc1)c1N1CC(N(CC2)Cc3c2cccc3)=O)C1=O

InChI

InChI=1S/C22H24N2O2/c1-15-8-9-19-18(12-15)22(2,3)21(26)24(19)14-20(25)23-11-10-16-6-4-5-7-17(16)13-23/h4-9,12H,10-11,13-14H2,1-3H3

InChI Key

FPJZFZCWEZRQRQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27116459

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.573

Distribution Coefficient, logD

3.573

Water Solubility, LogSw

-3.71

Polar Surface Area

31.761

Acid Dissociation Constant (pKa)

23.31

Base Dissociation Constant (pKb)

-2.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

F324-1265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with F324-1265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F324-1265?
Check Price and Availability of F324-1265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F324-1265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F324-1265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F324-1265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F324-1265 available by request