F327-0149 Screening compound: 1-(3-chlorophenyl)-3-[6-phenyl-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]urea

F327-0149 Screening compound: 1-(3-chlorophenyl)-3-[6-phenyl-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]urea
F327-0149 Screening compound: 1-(3-chlorophenyl)-3-[6-phenyl-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F327-0149
1-(3-chlorophenyl)-3-[6-phenyl-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F327-0149

Molecular Formula

C24H26ClN7OS (C24 H26 ClN7 OS)

Compound Name

1-(3-chlorophenyl)-3-[6-phenyl-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]urea

IUPAC name

1-(3-chlorophenyl)-3-[6-phenyl-2-(4-propylpiperazin-1-yl)imidazo[21-b][134]thiadiazol-5-yl]urea

SMILES

CCCN(CC1)CCN1c(s1)nn2c1nc(-c1ccccc1)c2NC(Nc1cccc(Cl)c1)=O

InChI

InChI=1S/C24H26ClN7OS/c1-2-11-30-12-14-31(15-13-30)24-29-32-21(28-22(33)26-19-10-6-9-18(25)16-19)20(27-23(32)34-24)17-7-4-3-5-8-17/h3-10,16H,2,11-15H2,1H3,(H2,26,28,33)

InChI Key

RIIBMAXLNPDIFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27116872

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.04

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.590

Distribution Coefficient, logD

4.720

Water Solubility, LogSw

-5.81

Polar Surface Area

60.543

Acid Dissociation Constant (pKa)

12.10

Base Dissociation Constant (pKb)

8.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

F327-0149 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with F327-0149 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F327-0149?
Check Price and Availability of F327-0149, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F327-0149 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F327-0149
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F327-0149
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F327-0149 available by request