F344-0396 Screening compound: 2-[1-(4-methylbenzoyl)piperidin-4-yl]-N-(4-phenylbutan-2-yl)acetamide

F344-0396 Screening compound: 2-[1-(4-methylbenzoyl)piperidin-4-yl]-N-(4-phenylbutan-2-yl)acetamide
F344-0396 Screening compound: 2-[1-(4-methylbenzoyl)piperidin-4-yl]-N-(4-phenylbutan-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F344-0396
2-[1-(4-methylbenzoyl)piperidin-4-yl]-N-(4-phenylbutan-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F344-0396

Molecular Formula

C25H32N2O2 (C25 H32 N2 O2)

Compound Name

2-[1-(4-methylbenzoyl)piperidin-4-yl]-N-(4-phenylbutan-2-yl)acetamide

IUPAC name

2-[1-(4-methylbenzoyl)piperidin-4-yl]-N-(4-phenylbutan-2-yl)acetamide

SMILES

CC(CCc1ccccc1)NC(CC(CC1)CCN1C(c1ccc(C)cc1)=O)=O

InChI

InChI=1S/C25H32N2O2/c1-19-8-12-23(13-9-19)25(29)27-16-14-22(15-17-27)18-24(28)26-20(2)10-11-21-6-4-3-5-7-21/h3-9,12-13,20,22H,10-11,14-18H2,1-2H3,(H,26,28)/t20-/m0/s1

InChI Key

QPWKFGZKLTZQTL-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD14951011

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.489

Distribution Coefficient, logD

4.489

Water Solubility, LogSw

-4.35

Polar Surface Area

40.528

Acid Dissociation Constant (pKa)

14.76

Base Dissociation Constant (pKb)

0.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

F344-0396 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Nuclear receptors
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F344-0396 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F344-0396?
Check Price and Availability of F344-0396, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F344-0396 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F344-0396
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F344-0396
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F344-0396 available by request