F344-1182 Screening compound: N-[2-(4-benzylpiperazin-1-yl)ethyl]-2-[1-(2-chlorobenzoyl)piperidin-4-yl]acetamide

F344-1182 Screening compound: N-[2-(4-benzylpiperazin-1-yl)ethyl]-2-[1-(2-chlorobenzoyl)piperidin-4-yl]acetamide
F344-1182 Screening compound: N-[2-(4-benzylpiperazin-1-yl)ethyl]-2-[1-(2-chlorobenzoyl)piperidin-4-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F344-1182
N-[2-(4-benzylpiperazin-1-yl)ethyl]-2-[1-(2-chlorobenzoyl)piperidin-4-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F344-1182

Molecular Formula

C27H35ClN4O2 (C27 H35 ClN4 O2)

Compound Name

N-[2-(4-benzylpiperazin-1-yl)ethyl]-2-[1-(2-chlorobenzoyl)piperidin-4-yl]acetamide

IUPAC name

N-[2-(4-benzylpiperazin-1-yl)ethyl]-2-[1-(2-chlorobenzoyl)piperidin-4-yl]acetamide

SMILES

O=C(CC(CC1)CCN1C(c(cccc1)c1Cl)=O)NCCN1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C27H35ClN4O2/c28-25-9-5-4-8-24(25)27(34)32-13-10-22(11-14-32)20-26(33)29-12-15-30-16-18-31(19-17-30)21-23-6-2-1-3-7-23/h1-9,22H,10-21H2,(H,29,33)

InChI Key

GJOAWZKZNLJSSM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14951255

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.05

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.567

Distribution Coefficient, logD

2.351

Water Solubility, LogSw

-3.53

Polar Surface Area

48.451

Acid Dissociation Constant (pKa)

13.60

Base Dissociation Constant (pKb)

7.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.10

F344-1182 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Proteases

References: we are preparing a list of scientific research reports with F344-1182 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F344-1182?
Check Price and Availability of F344-1182, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F344-1182 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F344-1182
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F344-1182
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F344-1182 available by request