F352-0008 Screening compound: 4-({5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}carbonyl)benzonitrile

F352-0008 Screening compound: 4-({5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}carbonyl)benzonitrile
F352-0008 Screening compound: 4-({5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}carbonyl)benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound F352-0008
4-({5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}carbonyl)benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F352-0008

Molecular Formula

C23H20N4O (C23 H20 N4 O)

Compound Name

4-({5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}carbonyl)benzonitrile

IUPAC name

4-({5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxalin]-1-yl}carbonyl)benzonitrile

SMILES

N#Cc(cc1)ccc1C(N(CC1)CCC11Nc(cccc2)c2-n2c1ccc2)=O

InChI

InChI=1S/C23H20N4O/c24-16-17-7-9-18(10-8-17)22(28)26-14-11-23(12-15-26)21-6-3-13-27(21)20-5-2-1-4-19(20)25-23/h1-10,13,25H,11-12,14-15H2

InChI Key

KZWWXEPDHKWIIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27117905

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.469

Distribution Coefficient, logD

3.469

Water Solubility, LogSw

-3.60

Polar Surface Area

47.450

Acid Dissociation Constant (pKa)

19.44

Base Dissociation Constant (pKb)

3.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

F352-0008 in Drug Discovery

Included in Screening Libraries

Human Ion Channels Annotated Library (353 compounds)

Integrin Receptors Targeted library (1715 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Nervous system
Targets:
  • Others
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F352-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F352-0008?
Check Price and Availability of F352-0008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F352-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F352-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F352-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F352-0008 available by request