F352-0542 Screening compound: 7'-fluoro-1-(furan-2-carbonyl)-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

F352-0542 Screening compound: 7'-fluoro-1-(furan-2-carbonyl)-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]
F352-0542 Screening compound: 7'-fluoro-1-(furan-2-carbonyl)-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline] alternative view

Chemical Structure Depiction of ChemDiv screening compound F352-0542
7'-fluoro-1-(furan-2-carbonyl)-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F352-0542

Molecular Formula

C20H18FN3O2 (C20 H18 FN3 O2)

Compound Name

7'-fluoro-1-(furan-2-carbonyl)-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

IUPAC name

7'-fluoro-1-(furan-2-carbonyl)-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxaline]

SMILES

O=C(c1ccco1)N(CC1)CCC11Nc(cc(cc2)F)c2-n2c1ccc2

InChI

InChI=1S/C20H18FN3O2/c21-14-5-6-16-15(13-14)22-20(18-4-1-9-24(16)18)7-10-23(11-8-20)19(25)17-3-2-12-26-17/h1-6,9,12-13,22H,7-8,10-11H2

InChI Key

MNWPREDHGSTSBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27117991

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.449

Distribution Coefficient, logD

3.449

Water Solubility, LogSw

-3.76

Polar Surface Area

38.972

Acid Dissociation Constant (pKa)

17.56

Base Dissociation Constant (pKb)

7.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

F352-0542 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F352-0542 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F352-0542?
Check Price and Availability of F352-0542, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F352-0542 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F352-0542
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F352-0542
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F352-0542 available by request