F352-0546 Screening compound: 1-{7'-fluoro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-3-(4-methoxyphenyl)propan-1-one

F352-0546 Screening compound: 1-{7'-fluoro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-3-(4-methoxyphenyl)propan-1-one
F352-0546 Screening compound: 1-{7'-fluoro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-3-(4-methoxyphenyl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F352-0546
1-{7'-fluoro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-3-(4-methoxyphenyl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F352-0546

Molecular Formula

C25H26FN3O2 (C25 H26 FN3 O2)

Compound Name

1-{7'-fluoro-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-3-(4-methoxyphenyl)propan-1-one

IUPAC name

1-{7'-fluoro-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxalin]-1-yl}-3-(4-methoxyphenyl)propan-1-one

SMILES

COc1ccc(CCC(N(CC2)CCC22Nc(cc(cc3)F)c3-n3c2ccc3)=O)cc1

InChI

InChI=1S/C25H26FN3O2/c1-31-20-8-4-18(5-9-20)6-11-24(30)28-15-12-25(13-16-28)23-3-2-14-29(23)22-10-7-19(26)17-21(22)27-25/h2-5,7-10,14,17,27H,6,11-13,15-16H2,1H3

InChI Key

IFGXYRMBFAEVPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27117994

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.602

Distribution Coefficient, logD

4.602

Water Solubility, LogSw

-4.31

Polar Surface Area

37.411

Acid Dissociation Constant (pKa)

17.56

Base Dissociation Constant (pKb)

2.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

F352-0546 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Spiro Library (21655 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Proteases
  • Ion Channels
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F352-0546 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F352-0546?
Check Price and Availability of F352-0546, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F352-0546 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F352-0546
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F352-0546
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F352-0546 available by request