F352-1440 Screening compound: 1-(2-fluorobenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

F352-1440 Screening compound: 1-(2-fluorobenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]
F352-1440 Screening compound: 1-(2-fluorobenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline] alternative view

Chemical Structure Depiction of ChemDiv screening compound F352-1440
1-(2-fluorobenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F352-1440

Molecular Formula

C24H24FN3O (C24 H24 FN3 O)

Compound Name

1-(2-fluorobenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

IUPAC name

1-(2-fluorobenzoyl)-8'9'-dimethyl-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxaline]

SMILES

Cc(cc1)c(C)c-2c1NC(CC1)(CCN1C(c(cccc1)c1F)=O)c1cccn12

InChI

InChI=1S/C24H24FN3O/c1-16-9-10-20-22(17(16)2)28-13-5-8-21(28)24(26-20)11-14-27(15-12-24)23(29)18-6-3-4-7-19(18)25/h3-10,13,26H,11-12,14-15H2,1-2H3

InChI Key

HLOORZLIUIQEHR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27118160

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.47

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.096

Distribution Coefficient, logD

5.094

Water Solubility, LogSw

-4.82

Polar Surface Area

31.551

Acid Dissociation Constant (pKa)

19.50

Base Dissociation Constant (pKb)

9.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

F352-1440 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with F352-1440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F352-1440?
Check Price and Availability of F352-1440, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F352-1440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F352-1440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F352-1440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F352-1440 available by request