F352-1458 Screening compound: 1-{8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-2-ethylbutan-1-one

F352-1458 Screening compound: 1-{8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-2-ethylbutan-1-one
F352-1458 Screening compound: 1-{8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-2-ethylbutan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F352-1458
1-{8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-2-ethylbutan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F352-1458

Molecular Formula

C23H31N3O (C23 H31 N3 O)

Compound Name

1-{8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxalin]-1-yl}-2-ethylbutan-1-one

IUPAC name

1-{8'9'-dimethyl-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxalin]-1-yl}-2-ethylbutan-1-one

SMILES

CCC(CC)C(N(CC1)CCC11Nc(ccc(C)c2C)c2-n2c1ccc2)=O

InChI

InChI=1S/C23H31N3O/c1-5-18(6-2)22(27)25-14-11-23(12-15-25)20-8-7-13-26(20)21-17(4)16(3)9-10-19(21)24-23/h7-10,13,18,24H,5-6,11-12,14-15H2,1-4H3

InChI Key

DJJWPYSABZSEBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27118174

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.52

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.513

Distribution Coefficient, logD

5.510

Water Solubility, LogSw

-5.27

Polar Surface Area

31.823

Acid Dissociation Constant (pKa)

19.50

Base Dissociation Constant (pKb)

5.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.17

F352-1458 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-infective Library (19449 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Immune system
  • animal
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with F352-1458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F352-1458?
Check Price and Availability of F352-1458, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F352-1458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F352-1458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F352-1458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F352-1458 available by request