F352-1463 Screening compound: 1-(4-ethoxybenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

F352-1463 Screening compound: 1-(4-ethoxybenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]
F352-1463 Screening compound: 1-(4-ethoxybenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline] alternative view

Chemical Structure Depiction of ChemDiv screening compound F352-1463
1-(4-ethoxybenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F352-1463

Molecular Formula

C26H29N3O2 (C26 H29 N3 O2)

Compound Name

1-(4-ethoxybenzoyl)-8',9'-dimethyl-5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]

IUPAC name

1-(4-ethoxybenzoyl)-8'9'-dimethyl-5'H-spiro[piperidine-44'-pyrrolo[12-a]quinoxaline]

SMILES

CCOc(cc1)ccc1C(N(CC1)CCC11Nc(ccc(C)c2C)c2-n2c1ccc2)=O

InChI

InChI=1S/C26H29N3O2/c1-4-31-21-10-8-20(9-11-21)25(30)28-16-13-26(14-17-28)23-6-5-15-29(23)24-19(3)18(2)7-12-22(24)27-26/h5-12,15,27H,4,13-14,16-17H2,1-3H3

InChI Key

DOIJBQPXEQEGRO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27118179

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.54

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.329

Distribution Coefficient, logD

5.327

Water Solubility, LogSw

-5.21

Polar Surface Area

38.675

Acid Dissociation Constant (pKa)

19.50

Base Dissociation Constant (pKb)

9.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

F352-1463 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with F352-1463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F352-1463?
Check Price and Availability of F352-1463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F352-1463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F352-1463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F352-1463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F352-1463 available by request