F356-0481 Screening compound: 1-[(3-fluorophenyl)methyl]-2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-1H-indole

F356-0481 Screening compound: 1-[(3-fluorophenyl)methyl]-2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-1H-indole
F356-0481 Screening compound: 1-[(3-fluorophenyl)methyl]-2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound F356-0481
1-[(3-fluorophenyl)methyl]-2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F356-0481

Molecular Formula

C20H18FN3O (C20 H18 FN3 O)

Compound Name

1-[(3-fluorophenyl)methyl]-2-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-1H-indole

IUPAC name

1-[(3-fluorophenyl)methyl]-2-[5-(propan-2-yl)-134-oxadiazol-2-yl]-1H-indole

SMILES

CC(C)c1nnc(-c2cc(cccc3)c3n2Cc2cccc(F)c2)o1

InChI

InChI=1S/C20H18FN3O/c1-13(2)19-22-23-20(25-19)18-11-15-7-3-4-9-17(15)24(18)12-14-6-5-8-16(21)10-14/h3-11,13H,12H2,1-2H3

InChI Key

QHFZGWOOGVHLHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08920232

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

335.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.026

Distribution Coefficient, logD

5.026

Water Solubility, LogSw

-5.32

Polar Surface Area

31.208

Acid Dissociation Constant (pKa)

25.81

Base Dissociation Constant (pKb)

-2.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

F356-0481 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F356-0481 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F356-0481?
Check Price and Availability of F356-0481, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F356-0481 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F356-0481
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F356-0481
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F356-0481 available by request