F357-0329 Screening compound: 3-(5-chloro-2-methylphenyl)-1-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]urea

F357-0329 Screening compound: 3-(5-chloro-2-methylphenyl)-1-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]urea
F357-0329 Screening compound: 3-(5-chloro-2-methylphenyl)-1-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F357-0329
3-(5-chloro-2-methylphenyl)-1-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F357-0329

Molecular Formula

C26H20Cl2N6O2 (C26 H20 Cl2 N6 O2)

Compound Name

3-(5-chloro-2-methylphenyl)-1-[4-({4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]urea

IUPAC name

3-(5-chloro-2-methylphenyl)-1-[4-({4-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]urea

SMILES

Cc(ccc(Cl)c1)c1NC(Nc1ccc(Cn2cnc(-c3nc(-c(cc4)ccc4Cl)no3)c2)cc1)=O

InChI

InChI=1S/C26H20Cl2N6O2/c1-16-2-7-20(28)12-22(16)31-26(35)30-21-10-3-17(4-11-21)13-34-14-23(29-15-34)25-32-24(33-36-25)18-5-8-19(27)9-6-18/h2-12,14-15H,13H2,1H3,(H2,30,31,35)

InChI Key

ZTYGOWYSGMPFCC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27118658

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

519.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.561

Distribution Coefficient, logD

6.561

Water Solubility, LogSw

-6.34

Polar Surface Area

75.313

Acid Dissociation Constant (pKa)

11.51

Base Dissociation Constant (pKb)

2.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.70

F357-0329 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with F357-0329 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F357-0329?
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What is the minimum amount of F357-0329 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F357-0329
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F357-0329
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F357-0329 available by request