F358-0318 Screening compound: 4-bromo-N-[4-({4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]benzamide

F358-0318 Screening compound: 4-bromo-N-[4-({4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]benzamide
F358-0318 Screening compound: 4-bromo-N-[4-({4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F358-0318
4-bromo-N-[4-({4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F358-0318

Molecular Formula

C25H17BrFN5O2 (C25 H17 BrFN5 O2)

Compound Name

4-bromo-N-[4-({4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]benzamide

IUPAC name

4-bromo-N-[4-({4-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-1H-imidazol-1-yl}methyl)phenyl]benzamide

SMILES

O=C(c(cc1)ccc1Br)Nc1ccc(Cn2cnc(-c3nc(-c4cc(F)ccc4)no3)c2)cc1

InChI

InChI=1S/C25H17BrFN5O2/c26-19-8-6-17(7-9-19)24(33)29-21-10-4-16(5-11-21)13-32-14-22(28-15-32)25-30-23(31-34-25)18-2-1-3-20(27)12-18/h1-12,14-15H,13H2,(H,29,33)

InChI Key

KFQXVRSWTPNODP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14951687

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

518.34

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.813

Distribution Coefficient, logD

5.812

Water Solubility, LogSw

-5.93

Polar Surface Area

66.799

Acid Dissociation Constant (pKa)

10.15

Base Dissociation Constant (pKb)

2.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.00

F358-0318 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with F358-0318 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F358-0318?
Check Price and Availability of F358-0318, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F358-0318 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F358-0318
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F358-0318
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F358-0318 available by request