F360-0400 Screening compound: methyl 4-[(6-chloro-3-cyanoquinolin-4-yl)amino]benzoate

F360-0400 Screening compound: methyl 4-[(6-chloro-3-cyanoquinolin-4-yl)amino]benzoate
F360-0400 Screening compound: methyl 4-[(6-chloro-3-cyanoquinolin-4-yl)amino]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound F360-0400
methyl 4-[(6-chloro-3-cyanoquinolin-4-yl)amino]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F360-0400

Molecular Formula

C18H12ClN3O2 (C18 H12 ClN3 O2)

Compound Name

methyl 4-[(6-chloro-3-cyanoquinolin-4-yl)amino]benzoate

IUPAC name

methyl 4-[(6-chloro-3-cyanoquinolin-4-yl)amino]benzoate

SMILES

COC(c(cc1)ccc1Nc1c(cc(cc2)Cl)c2ncc1C#N)=O

InChI

InChI=1S/C18H12ClN3O2/c1-24-18(23)11-2-5-14(6-3-11)22-17-12(9-20)10-21-16-7-4-13(19)8-15(16)17/h2-8,10H,1H3,(H,21,22)

InChI Key

QNESHGPVBZXBLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11995323

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

337.77

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.234

Distribution Coefficient, logD

4.234

Water Solubility, LogSw

-4.56

Polar Surface Area

54.838

Acid Dissociation Constant (pKa)

14.37

Base Dissociation Constant (pKb)

3.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

F360-0400 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F360-0400 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F360-0400?
Check Price and Availability of F360-0400, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F360-0400 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F360-0400
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F360-0400
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F360-0400 available by request