F362-0894 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

F362-0894 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine
F362-0894 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F362-0894
3-[(4-chlorophenyl)sulfanyl]-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F362-0894

Molecular Formula

C25H27ClN6OS (C25 H27 ClN6 OS)

Compound Name

3-[(4-chlorophenyl)sulfanyl]-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

IUPAC name

3-[(4-chlorophenyl)sulfanyl]-6-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}pyridazine

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1Sc(cc1)ccc1Cl)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C25H27ClN6OS/c26-20-4-6-21(7-5-20)34-24-9-8-23(28-29-24)30-13-10-19(11-14-30)25(33)32-17-15-31(16-18-32)22-3-1-2-12-27-22/h1-9,12,19H,10-11,13-18H2

InChI Key

NDHONMGGDWIERC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119190

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.05

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.003

Distribution Coefficient, logD

4.994

Water Solubility, LogSw

-5.20

Polar Surface Area

52.407

Acid Dissociation Constant (pKa)

22.96

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

F362-0894 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F362-0894 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F362-0894?
Check Price and Availability of F362-0894, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F362-0894 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F362-0894
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F362-0894
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F362-0894 available by request