F362-1686 Screening compound: 1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

F362-1686 Screening compound: 1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide
F362-1686 Screening compound: 1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F362-1686
1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F362-1686

Molecular Formula

C22H22FN5OS (C22 H22 FN5 OS)

Compound Name

1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-{6-[(3-fluorophenyl)sulfanyl]pyridazin-3-yl}-N-[(pyridin-3-yl)methyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(cc1)nnc1Sc1cc(F)ccc1)NCc1cnccc1

InChI

InChI=1S/C22H22FN5OS/c23-18-4-1-5-19(13-18)30-21-7-6-20(26-27-21)28-11-8-17(9-12-28)22(29)25-15-16-3-2-10-24-14-16/h1-7,10,13-14,17H,8-9,11-12,15H2,(H,25,29)

InChI Key

YYDBSUGMBRGLAG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27119207

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.883

Distribution Coefficient, logD

2.881

Water Solubility, LogSw

-3.06

Polar Surface Area

57.918

Acid Dissociation Constant (pKa)

13.36

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

F362-1686 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with F362-1686 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F362-1686?
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What is the minimum amount of F362-1686 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F362-1686
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F362-1686
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F362-1686 available by request